CuBiAn Analyzer, Reagents And Beads Products

Bioprocess Monitoring

With its history and background, Optocell is dedicated to the upstream bioprocess monitoring ever since. Its Culture Biochemistry Analyzer „CuBiAn“ offers a complete solution in combination with the optimized reagent kits for the easy and fast determination of substrates, metabolites and products. In R&D, process development and GMP laboratories the photometric CuBiAn system has already proven its reliability over membrane-based analyzers.

It is an optimal solution combining high-throughput application and a system, which has the smallest footprint in its class. The BioMajesty is designed to increase performance in your laboratory.

  • Benefits
  • flexibility in everyday use
  • secured results & highest possible precision
  • user friendliness
  • save of precious laboratory space
  • optimized workflow
  • no additional dilutions needed
  • low sample & reagent consumption
  • economic usage
  • designed to run 24/7
  • cost efficiency
BioMajesty

Please follow the next link to get more in depth informations!

More information

The CuBiAn HT270 is a fully automated biochemistry analyzer in benchtop size for the determination of substrates, metabolites and products in cell culture and fermentation samples. Benefits:

  • Quality
  • Proven photometric technology provides better accuracy, precision and linearity compared to membrane technology
  • Low calibration frequency guarantees high reproducibility
  • Use of barcoded reagents provides consistent traceability of lots
  • Handling
  • Unattended measurement due to preprogramming cycles
  • Easy handling as reagents are barcoded, liquid stable and ready to use
  • Auto-rerun option for dilution
  • Easy change of lots as up to 2 different lots per parameter can be used at once
  • Value
  • Very low minimum sample volumes
  • Cost-saving through low maintenance and semi-disposable cuvettes
  • Designed to run 24/7
  • Continuous extension of parameters on one system
  • CFR Part 11 compliance
CuBiAn HT270

Please follow the next link to get more in depth informations!

More information

Optocell offers more than 20 optimized reagents for every day routine and for special parameters of upstream bioprocess monitoring. The reagents are liquid-stable and ready-to-use, show excellent stability and outstanding performance. Optocell reagents are provided in optimized kits for CuBiAn systems.

  • Benefits
  • Easy handling with ready-to-use reagents.
  • Outstanding reproducibility within and between lots due to liquid reagents, avoiding errors which can be caused by reinverting lyophilized reagents.
  • Long on-board stability of at least 30 days for the majority of reagents.
  • Easy lot traceability with barcoded bottles, containing the information and transferring it to the system.
  • No ISE-Module necessary. Sodium, Potassium and Chloride are available as photometric assays.

Cell Counting

With many years of experience in the field of cell counting, Optocell offers its own product line of particle solutions for the system suitability tests for Cedex and Cedex HiRes* systems. Our in-depth knowledge about the systems helped us to optimize the products to create an added value for the customer.

*Cedex and Cedex HiRes are trademarks of Roche

ConSta 1.0 is a certified suspension of mono dispersal polystyrene beads to verify the concentration accuracy of particle - or cell analyzers, based on image recognition. ConSta 1.0 can be used according to the standard operating procedures of the instrument supplier. Each single bottle of ConSta 1.0 is certified by triplicate analysis and fulfills highest requirements in terms of quality.

  • Benefits
  • Particle Concentration Standard produced in compliance to international QA regulations
  • Traceable to official norm standards [NIST, PTB]
  • Applicable to various cell analyzers based on image recognition
  • Provides confirmation of the accuracy and precision of the measurement results
  • Tool for comparison trials of technically equivalent systems
  • Optimized volume adapted to practice and optimized liquid composition (reduced foam formation)
  • Product Details
  • Designated application: Calibration and adjustment of cell analyzers based on image recognition
  • Characteristics: Suspension of mono dispersal polystyrene beads
  • Designed and produced following the guidelines of GMP
  • Tracing by: PTB Berlin Germany (Federal Institute of Physics and Technology)
  • Nominal concentration: 1.0 x 106 beads per mL
  • Actual concentration of each bottle is certified by a Certificate of Analysis
  • Particle dimensions: 10 µm (±3 %)
  • Content: 6.5 mL
Article No. Product
300001 ConSta 1.0 Batch A, 6.5 mL (1.0 x 106 B/mL)
300002 ConSta 1.0 Batch B, 6.5 mL (1.0 x 106 B/mL)
300003 ConSta 1.0 Batch A and Batch B, 2 x 6.5 mL
Download Description
Download ConSta 1.0 Certificate of Analysis
Download ConSta PTB
*Cedex and Cedex HiRes are trademarks of Roche

LinSta are certified control suspensions of beads to verify the linearity of calibration curves in cell analyzers, based on image recognition (Cedex and Cedex HiRes*). LinSta can be used according to the standard operating procedures of the instrument supplier. LinSta is an easy-to-handle, but sophisticated tool to monitor system suitability. Each lot of LinSta is certified by triplicate analysis.

  • Benefits
  • Universal Linearity Standard, produced in compliance to international QA regulations
  • Tool for testing the System’s Suitability in daily routine lab work
  • Product range covers typical cell concentrations of bio processes
  • Applicable to various cell analyzers
  • LinSta complements ConSta 1.0 at the System Suitability Test
  • Determination of the "device density value" is not required
  • Product Details
  • Designated application: Linearity control of concentration adjustment curves in cell analyzers based on image recognition
  • Suspension of beads with cell-like optical characteristics
  • Produced according to guidelines of GMP
  • Tracing by: Optocell GmbH & Co. KG, Bielefeld, Germany
  • Nominal concentrations: 0.5 x 106 - 7.5 x 106 beads per mL
  • Particle dimensions: 4 - 17 µm
  • Content: 20 mL per bottle
  • Selections of various concentrations available
Article No. Product
300008 LinSta 0.5 (0.5 x 106 B/mL)
300009 LinSta.1.0 (1.0 x 106 B/mL)
300010 LinSta 2.5 (2.5 x 106 B/mL)
300011 LinSta 5.0 (5.0 x 106 B/mL)
300012 LinSta 7.5 (7.5 x 106 B/mL)
*Cedex and Cedex HiRes are trademarks of Roche

FocSta 2.5 is a suspension of beads designed for adjustment of optical components of a variety of image recognition systems. FocSta 2.5 can be used according to the standard operating procedures of the instruments supplier. Each lot of FocSta 2.5 is certified by triplicate analysis.

  • Benefits
  • Standardized Particle Suspension - compliant to international QA regulations
  • Tool for adjustment of focus and illumination in optical based systems
  • Applicable to various cell analyzers
  • Easy to use
  • Optimized volume per bottle
  • Product Details
  • Designated application: Automated adjustment of focus and illumination of cell analyzers, based on image recognition
  • Characteristics: Suspension of beads with varying diameters
  • Designed and produced following the guidelines of GMP
  • Tracing by: Optocell GmbH & Co. KG, Bielefeld, Germany
  • Particle dimensions: from 4 -17 µm
  • Content: 6 mL per bottle
Article No. Product
300007 FocSta 2.5
*Cedex and Cedex HiRes are trademarks of Roche

ViaSta is a certified suspension of beads to check viability in cell analyzers, based on image recognition. ViaSta can be used according to the standard operating procedures of the instrument supplier. ViaSta is part of the system suitability test and allows for checking the status of the optical hardware components. Each lot of ViaSta is certified by triplicate analysis.

  • Benefits
  • Universal Viability Standard produced in compliance to international QA regulations
  • Tool for testing the System’s Suitability in daily routine lab work
  • Detection of image recognition malfunction at an early stage
  • Control of illumination status and focus position
  • Powerful tool for Service & Support for determining the possible source of malfunction in the system
  • Applicable to various cell analyzers
  • ViaSta complements LinSta and ConSta at the System Suitability Test
  • Product Details
  • Designated application: Viability control of cell analyzers based on image recognition
  • Suspension of beads with cell-like optical characteristics
  • Produced according to guidelines of GMP
  • Tracing by: Optocell GmbH & Co. KG, Bielefeld, Germany
  • Optical viability level: 100%, 80%, 60% and 30%
  • Particle dimensions: 4 - 17 µm
  • Content: 10 mL per bottle
Article No. Product
300013 ViaSta 1.0 (100%)
300014 ViaSta 0.8 (80%)
300015 ViaSta 0.6 (60%)
300016 ViaSta 0.3 (30%)
*Cedex and Cedex HiRes are trademarks of Roche

Batch Certified Linearity Standards with nominal concentration of 1.0 x 106 beads/mL

Product Features

LinSta EASY is a certified control suspension of beads to verify the linearity of calibration curves 
of CASY* Cell Counters. LinSta EASY can be used according to the standard operating procedures of the instrument supplier. LinSta EASY is an easy-to-handle, but sophisticated tool to monitor system suitability. Each lot of LinSta EASY is certified by triplicate analysis.

  • Benefits
  • Universal Linearity Standard, produced in compliance to international QA regulations
  • Tool for testing the System’s Suitability in daily routine lab work
  • Product covers typical cell concentration of bio processes
  • Product Details
  • Designated application: Linearity control to check measurement performance of a CASY* system at regular intervals
  • Suspension of beads with cell-like optical characteristics
  • Produced according to guidelines of GMP
  • Tracing by: Optocell GmbH & Co. KG, Bielefeld, Germany
  • Nominal concentration: 1.0 x 106 beads per mL
  • Particle dimensions: 4 - 17 µm
  • Content: 5 mL per bottle
Article No. Product
300017 LinSta EASY (1.0 x 106 B/mL)
*CASY is a trademark of OMNI Life Science